Reducing Exposure To Particulates Improves Cardiovascular...

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Reducing Exposure To Particulates Improves Cardiovascular...

Postby Wilberforce » Thu Jan 05, 2012 12:58 pm

Reducing Personal Exposure To Particulate Air Pollution Improves Cardiovascular Health
In Patients With Coronary Heart Disease


Jeremy P. Langrish, Xi Li, Shengfeng Wang, Matthew MY. Lee, Gareth D. Barnes, Mark R. Miller, Flemming R. Cassee, Nicholas A. Boon, Ken Donaldson, Jing Li, Liming Li, Nicholas L. Mills, David E. Newby, Lixin Jiang
http://ehp03.niehs.nih.gov/article/info ... hp.1103898

Abstract Top

Background. Air pollution exposure increases cardiovascular morbidity and mortality, and is a major global public health concern.

Objectives. To investigate the benefits of reducing personal exposure to urban air pollution in patients with coronary heart disease.

Methods. In an open randomised crossover trial, 98 patients with coronary heart disease walked on a pre-defined route in central Beijing, China on two occasions, once while using a highly efficient facemask and once while not using the mask. Symptoms, exercise, personal air pollution exposure, blood pressure, heart rate and 12-lead electrocardiography were monitored throughout the 24-hour study period.

Results. Ambient air pollutants were dominated by fine and ultrafine particles that were present at high levels (74 µg/m3 for particulate matter <2.5 µm). Consistent with traffic-derived sources, this particulate matter contained organic carbon and polycyclic aromatic hydrocarbons, and was highly oxidising generating large amounts of free radicals. The facemask was well tolerated, and use was associated with decreased self-reported symptoms and reduced maximal ST segment depression (-142 vs. -156 µV, P=0.046) over the 24-hour period. When the mask was used, mean arterial pressure was lower (93±10 vs. 96±10 mmHg; P=0.025) and heart rate variability increased (HF-power 54 vs 40 ms2, P=0.005; HFn 23.5 vs 20.5 ms, P=0.001; RMSSD 16.7 vs 14.8 ms, P=0.007) during the prescribed walk, but mask use did not appear to influence heart rate or energy expenditure.

Conclusions. Reducing personal exposure to air pollution using a highly efficient facemask appeared to reduce symptoms and improve a range of cardiovascular health measures in patients with coronary heart disease. Such interventions to reduce personal exposure to particulate air pollution have the potential to reduce the incidence of cardiovascular events in this highly susceptible population.


Citation: Langrish JP, Li X, Wang S, Lee MM, Barnes GD, Miller MR, et al. 2012. Reducing Personal Exposure To Particulate Air Pollution Improves Cardiovascular Health In Patients With Coronary Heart Disease. Environ Health Perspect :-. http://dx.doi.org/10.1289/ehp.1103898

Received: 05 May 2011; Accepted: 03 January 2012; Online: 03 January 2012
• The Surgeon General has determined that there is no safe level of exposure to ambient smoke!

• If you smell even a subtle odor of smoke, you are being exposed to poisonous and carcinogenic chemical compounds!

• Even a brief exposure to smoke raises blood pressure, (no matter what your state of health) and can cause blood clotting, stroke, or heart attack in vulnerable people. Even children experience elevated blood pressure when exposed to smoke!

• Since smoke drastically weakens the lungs' immune system, avoiding smoke is one of the best ways to prevent colds, flu, bronchitis, or risk of an even more serious respiratory illness, such as pneumonia or tuberculosis!
Does your child have the flu? Chances are they have been exposed to ambient smoke!
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