Exposure to wood smoke particles produces inflammation...

Research studies on wood smoke and other air pollution.

Exposure to wood smoke particles produces inflammation...

Postby Wilberforce » Sun Feb 12, 2012 2:57 pm

Exposure to wood smoke particles produces inflammation in healthy volunteers
http://oem.bmj.com/content/69/3/170.short?rss=1
Andrew J Ghio1,
Joleen M Soukup1,
Martin Case1,
Lisa A Dailey1,
Judy Richards1,
Jon Berntsen2,
Robert B Devlin1,
Susan Stone1,
Ana Rappold1

+ Author Affiliations

1The National Health and Environmental Effects Research Laboratory, US EPA, Research Triangle Park, North Carolina, USA
2TRC Environmental, Chapel Hill, North Carolina, USA

Correspondence to Andrew Ghio, Environmental Public Health Division, HSF, US EPA, Campus Box 7315, 104 Mason Farm Road, Chapel Hill, NC 27711, USA; ghio.andy@epa.gov

Accepted 8 June 2011
Published Online First 30 June 2011

Abstract

Objectives Human exposure to wood smoke particles (WSP) impacts on human health through changes in indoor air quality, exposures from wild fires, burning of biomass and air pollution. This investigation tested the postulate that healthy volunteers exposed to WSP would demonstrate evidence of both pulmonary and systemic inflammation.

Methods Ten volunteers were exposed to filtered air and, 3 weeks or more later, WSP. Each exposure included alternating 15 min of exercise and 15 min of rest for a total duration of 2 h. Wood smoke was generated by heating an oak log on an electric element and then delivered to the exposure chamber. Endpoints measured in the volunteers included symptoms, pulmonary function tests, measures of heart rate variability and repolarisation, blood indices and analysis of cells and fluid obtained during bronchoalveolar lavage.

Results Mean particle mass for the 10 exposures to air and WSP was measured using the mass of particles collected on filters and found to be below the detectable limit and 485±84 μg/m3, respectively (mean±SD). There was no change in either symptom prevalence or pulmonary function with exposure to WSP. At 20 h after wood smoke exposure, blood tests demonstrated an increased percentage of neutrophils, and bronchial and bronchoalveolar lavage revealed a neutrophilic influx.

Conclusions We conclude that exposure of healthy volunteers to WSP may be associated with evidence of both systemic and pulmonary inflammation.
• The Surgeon General has determined that there is no safe level of exposure to ambient smoke!

• If you smell even a subtle odor of smoke, you are being exposed to poisonous and carcinogenic chemical compounds!

• Even a brief exposure to smoke raises blood pressure, (no matter what your state of health) and can cause blood clotting, stroke, or heart attack in vulnerable people. Even children experience elevated blood pressure when exposed to smoke!

• Since smoke drastically weakens the lungs' immune system, avoiding smoke is one of the best ways to prevent colds, flu, bronchitis, or risk of an even more serious respiratory illness, such as pneumonia or tuberculosis!
Does your child have the flu? Chances are they have been exposed to ambient smoke!
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