Wood Smoke and COPD

Research studies on wood smoke and other air pollution.

Wood Smoke and COPD

Postby Wilberforce » Mon Jun 30, 2014 8:01 pm

Wood Smoke and COPD
FEV1 inversely correlates with metalloproteinases 1, 7, 9 and CRP in COPD by biomass smoke exposure
http://respiratory-research.com/content ... -15-74.pdf
Matrix metalloproteinases (MMPs) and C-reactive protein (CRP) are involved in chronic
obstructive pulmonary disease (COPD) pathogenesis. The aim of the present work was to
determine plasma concentrations of MMPs and CRP in COPD associated to biomass
combustion exposure (BE) and tobacco smoking (TS).

Pulmonary function tests, plasma levels of MMP-1, MMP-7, MMP-9, MMP-9/TIMP-1 and
CRP were measured in COPD associated to BE (n = 40) and TS (n =40) patients, and healthy
non-smoking (NS) healthy women (controls, n = 40).

Plasma levels of MMP-1, MMP-7, MMP-9, and MMP-9/TIMP-1 and CRP were higher in BE
and TS than in the NS healthy women (p <0.01). An inverse correlation between MMP-1,
MMP-7, MMP-9, MMP-9/TIMP-1 and CRP plasma concentrations and FEV1 was observed.

Increase of MMPs and CRP plasma concentrations in BE suggests a systemic inflammatory
phenomenon similar to that observed in COPD associated to tobacco smoking, which may
also play a role in COPD pathogenesis
• The Surgeon General has determined that there is no safe level of exposure to ambient smoke!

• If you smell even a subtle odor of smoke, you are being exposed to poisonous and carcinogenic chemical compounds!

• Even a brief exposure to smoke raises blood pressure, (no matter what your state of health) and can cause blood clotting, stroke, or heart attack in vulnerable people. Even children experience elevated blood pressure when exposed to smoke!

• Since smoke drastically weakens the lungs' immune system, avoiding smoke is one of the best ways to prevent colds, flu, bronchitis, or risk of an even more serious respiratory illness, such as pneumonia or tuberculosis! Does your child have the flu? Chances are they have been exposed to ambient smoke!
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